Federal agents are set to conduct a major immigration crackdown called “Swamp Sweep” in New Orleans in the coming weeks.

Around 250 federal border agents are set to descend on New Orleans in the coming weeks for a two-month immigration crackdown dubbed “Swamp Sweep” that aims to arrest roughly 5,000 people across southeast Louisiana and into Mississippi, according to documents obtained by The Associated Press and three people familiar with the operation.

The deployment, which is expected to begin in earnest on Dec. 1, marks the latest escalation in a series of rapid-fire immigration crackdowns unfolding nationwide — from Chicago to Los Angeles to Charlotte, North Carolina — as the Trump administration moves aggressively to fulfill the president’s campaign promise of mass deportations.

In Louisiana, the operation is unfolding on the home turf of Republican Gov. Jeff Landry, a close Trump ally who has moved to align state policy with the White House’s enforcement agenda. But, as seen in other blue cities situated in Republican-led states, increased federal enforcement presence could set up a collision with officials in liberal New Orleans who have long resisted federal sweeps.

Planning documents reviewed by the AP show Border Patrol teams preparing to fan out across neighborhoods and commercial hubs throughout southeast Louisiana, stretching from New Orleans through Jefferson, St. Bernard and St. Tammany parishes and as far north as Baton Rouge, with additional activity planned in southeastern Mississippi.

Agents are expected to arrive in New Orleans on Friday to begin staging equipment and vehicles before the Thanksgiving holiday, according to the people familiar with the operation. They are scheduled to return toward the end of the month, with the full sweep beginning in early December. The people familiar with the matter could not publicly discuss details of the operation and spoke to the AP on condition of anonymity.

Once “Swamp Sweep” begins, Louisiana will become a major testing ground for the administration’s expanding deportation strategy, and a focal point in the widening rift between federal authorities intent on carrying out large-scale arrests and city officials who have long resisted them.